Chromosome abnormalities in acute promyelocytic leukemia (APL)

Acute Promyelocytic Leukemia (APL)

Cost of Treating Acute Promyelocytic Leukemia (APL) Patients in Italy.

Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations.

Acute promyelocytic leukemia (APL) is a hematopoietic malignant disease characterized by the chromosomal translocation t(15;17), resulting in the formation of the PML-RARA gene. Here, 47 t(15;17) APL samples were analyzed with high-density single-nucleotide polymorphism microarray (50-K and 250-K SNP-chips) using the new algorithm AsCNAR (allele-specific copy-number analysis using anonymous ref...

Acute Promyelocytic Leukemia (APL): Comparison Between Children and Adults

The outcome of adults and children with Acute Promyelocytic Leukemia (APL) has dramatically changed since the introduction of all trans retinoic acid (ATRA) therapy. Based on the results of several multicenter trials, the current recommendations for the treatment of patients with APL include ATRA and anthracycline-based chemotherapy for the remission induction and consolidation, and ATRA combin...

Plenary Paper Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL Eduardo M. Rego, Haesook T. Kim, Guillermo J. Ruiz-Argüelles, Maria Soledad Undurraga, Maria del Rosario Uriarte, Rafael H. Jacomo, Homero Gutiérrez-Aguirre, Raul A. M. Melo, Rosane Bittencourt, Ricardo Pasquini, Katia Pagnano, Evandro M. Fagundes, Mari...